La Loire arrose 12 départements :
Allier (03), Ardèche (07), Cher (18), Indre et Loire (37), Loir et Cher (41), Loire (42), Haute Loire (43), Loire Atlantique (44), Loiret (45), Maine et Loire (49), Nièvre (58), Saône et Loire (71)

et 336 communes :

amboise (37003), ancenis (44003), andrezieux-boutheon (42005), anetz (44004), arlempdes (43008), artaix (71012), aurec-sur-loire (43012), avaray (41008), avril-sur-loire (58020), avrilly (03014), balbigny (42011), bannay (18020), bas-en-basset (43020), basse-goulaine (44009), baugy (71024), baule (45024), beard (58025), beaugency (45028), beaulieu (43021), beaulieu-sur-loire (45029), beaulon (03019), beaux (43024), beauzac (43025), beffes (18025), behuard (49028), belleville-sur-loire (18026), berthenay (37025), blaison-gohier (49029), blanzac (43030), blois (41018), boisset-les-montrond (42020), bonny-sur-loire (45040), bonson (42022), bou (45043), bouchemaine (49035), bouguenais (44020), boulleret (18032), bourbon-lancy (71047), bourg-le-comte (71048), brehemont (37038), briare (45053), briennon (42026), brives-charensac (43041), bully (42027), caloire (42031), cande-sur-beuvron (41029), cangey (37043), chadrac (43046), chadron (43047), chailles (41032), chaingy (45067), chalain-le-comtal (42038), challuy (58051), chalonnes-sur-loire (49063), chamalieres-sur-loire (43049), chambeon (42041), chambilly (71077), chambles (42042), champtoce-sur-loire (49068), champtoceaux (49069), charge (37060), charrin (58060), chaspinhac (43061), chassenard (03063), chateauneuf-sur-loire (45082), chatillon-sur-loire (45087), chaumont-sur-loire (41045), checy (45089), chenehutte-treves-cunault (49094), chevenon (58072), chouze-sur-loire (37074), chouzy-sur-cisse (41055), cinq-mars-la-pile (37077), cleppe (42066), combleux (45100), commelle-vernay (42069), cordelle (42070), cordemais (44045), cosne-cours-sur-loire (58086), cossaye (58087), couargues (18074), coubon (43078), coueron (44047), coulanges (03086), cour-sur-loire (41069), courbouzon (41066), cours-les-barres (18075), craintilleux (42075), cronat (71155), cros-de-georand (07075), cuffy (18082), cussac-sur-loire (43084), dampierre-en-burly (45122), dance (42082), decize (58095), denee (49120), devay (58096), digoin (71176), diou (03100), dompierre-sur-besbre (03102), druy-parigny (58105), epercieux-saint-paul (42088), feurs (42094), fleury-sur-loire (58115), fondettes (37109), fourchambault (58117), frossay (44061), gannay-sur-loire (03119), garchizy (58121), garnat-sur-engievre (03120), gennes (49149), germigny-des-pres (45153), germigny-sur-loire (58124), gien (45155), gilly-sur-loire (71220), gimouille (58126), goudet (43101), guilly (45164), herry (18110), iguerande (71238), imphy (58134), indre (44074), ingrandes (49160), issarles (07106), jargeau (45173), jouet-sur-l'aubois (18118), juigne-sur-loire (49167), l'hopital-le-mercier (71233), la bohalle (49032), la celle-sur-loire (58044), la chapelle-aux-naux (37056), la chapelle-basse-mer (44029), la chapelle-d'aurec (43058), la chapelle-montlinard (18049), la chapelle-saint-mesmin (45075), la chapelle-sur-loire (37058), la charite-sur-loire (58059), la chaussee-saint-victor (41047), la dagueniere (49117), la marche (58155), la menitre (49201), la motte-saint-jean (71325), la possonniere (49247), la riche (37195), la varenne (49360), lachapelle-graillouse (07121), lafarre (43109), lailly-en-val (45179), lamenay-sur-loire (58137), langeais (37123), lavoute-sur-loire (43119), le brignon (43039), le cellier (44028), le fresne-sur-loire (44060), le lac-d'issarles (07119), le marillais (49190), le mesnil-en-vallee (49204), le monteil (43140), le pellerin (44120), le thoureil (49346), lere (18125), les ponts-de-ce (49246), les rosiers-sur-loire (49261), limeray (37131), lion-en-sullias (45184), lire (49177), luneau (03154), lussault-sur-loire (37138), luthenay-uxeloup (58148), luynes (37139), mably (42127), magneux-haute-rive (42130), malvalette (43127), marcigny (71275), marclopt (42135), mardie (45194), mareau-aux-pres (45196) , marseilles-les-aubigny (18139), marzy (58160), mauves-sur-loire (44094), melay (71291), menars (41134), menetreol-sous-sancerre (18146), mesves-sur-loire (58164), meung-sur-loire (45203), mizerieux (42143), molinet (03173), monistrol-sur-loire (43137), montjean-sur-loire (49212), montlivault (41148), montlouis-sur-loire (37156), montrelais (44104), montrond-les-bains (42149), montsoreau (49219), mosnes (37161), muides-sur-loire (41155), myennes (58187), nantes (44109), nazelles-negron (37163), nervieux (42155), neuvy-sur-loire (58193), nevers (58194), nevoy (45227), noizay (37171), onzain (41167), orleans (45234), oudon (44115), ousson-sur-loire (45238), ouvrouer-les-champs (45241), ouzouer-sur-loire (45244), parnay (49235), perreux (42170), perrigny-sur-loire (71348), pierrefitte-sur-loire (03207), pinay (42171), poce-sur-cisse (37185), poilly-lez-gien (45254), polignac (43152), pouilly-sous-charlieu (42177), pouilly-sur-loire (58215), retournac (43162), rigny-usse (37197), rilly-sur-loire (41189), rivas (42185), roanne (42187), roche-en-regnier (43164), rochecorbon (37203), rochefort-sur-loire (49259), sagnes-et-goudoulet (07203), saint-agnan (71382), saint-aignan-le-jaillard (45268), saint-aubin-sur-loire (71389), saint-ay (45269), saint-benoit-sur-loire (45270), saint-brisson-sur-loire (45271), saint-cirgues-en-montagne (07224), saint-claude-de-diray (41204), saint-clement-des-levees (49272), saint-cyprien (42211), saint-cyr-sur-loire (37214), saint-denis-de-l'hotel (45273), saint-denis-en-val (45274), saint-denis-sur-loire (41206), saint-dye-sur-loire (41207), saint-eloi (58238), saint-etienne (42218), saint-etienne-de-chigny (37217), saint-etienne-de-montluc (44158), saint-firmin-sur-loire (45276), saint-florent-le-vieil (49276), saint-georges-de-baroille (42226), saint-germain-laprade (43190), saint-gondon (45280), saint-herblain (44162), saint-herblon (44163), saint-hilaire-fontaine (58245), saint-jean-de-boiseau (44166), saint-jean-de-braye (45284), saint-jean-de-la-croix (49288), saint-jean-de-la-ruelle (45285), saint-jean-des-mauvrets (49290), saint-jean-saint-maurice-sur-loire (42239), saint-jodard (42241), saint-julien-de-concelles (44169), saint-just-saint-rambert (42279), saint-laurent-du-mottay (49297), saint-laurent-la-conche (42251), saint-laurent-nouan (41220), saint-leger-des-vignes (58250), saint-leger-le-petit (18220), saint-marcel-de-felines (42254), saint-martin-de-fugeres (43210), saint-martin-de-la-place (49304), saint-martin-des-lais (03245), saint-martin-du-lac (71453), saint-martin-sur-ocre (45291), saint-mathurin-sur-loire (49307), saint-maurice-de-lignon (43211), saint-maurice-en-gourgois (42262), saint-michel-sur-loire (37227), saint-nizier-sous-charlieu (42267), saint-ouen-sur-loire (58258), saint-patrice (37232), saint-paul-de-vezelin (42268), saint-paul-en-cornillon (42270), saint-pere-sur-loire (45297), saint-pierre-des-corps (37233), saint-pierre-la-noaille (42273), saint-priest-la-roche (42277), saint-pryve-saint-mesmin (45298), saint-remy-la-varenne (49317), saint-satur (18233), saint-saturnin-sur-loire (49318), saint-sebastien-sur-loire (44190), saint-vincent (43230), sainte-eulalie (07235), sainte-gemmes-sur-loire (49278), sainte-luce-sur-loire (44172), salettes (43231), sandillon (45300), saumur (49328), sauvigny-les-bois (58273), savennieres (49329), savigny-en-veron (37242), sermoise-sur-loire (58278), sigloy (45311), solignac-sur-loire (43241), sougy-sur-loire (58280), souzay-champigny (49341), suevres (41252), sully-sur-loire (45315), sury-pres-lere (18257), tavers (45317), thouare-sur-loire (44204), tours (37261), tracy-sur-loire (58295), tronsanges (58298), unias (42315), unieux (42316), usclades-et-rieutord (07326), varades (44213), varenne-saint-germain (71557), varennes-sur-loire (49361), veauchette (42324), vernou-sur-brenne (37270), veuves (41272), vielprat (43263), villandry (37272), villebernier (49374), villerest (42332), vindecy (71581), vineuil (41295), vitry-sur-loire (71589), vorey (43267), vougy (42338), vouvray (37281)